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https://locus.ufv.br//handle/123456789/21315
Tipo: | Artigo |
Título: | Calix[n]arenes: active organocatalysts for the synthesis of densely functionalized piperidines by one-pot multicomponent procedure |
Autor(es): | Liberto, N. Palermo, V. Sathicq, A. Fernandes, S. Langer, P. Jios, J. Romanelli, G. |
Abstract: | An efficient, suitable and high yielding method has been developed for the synthesis of different densely functionalized piperidine derivatives via pseudo-five component, one-pot domino reaction through a combination of b-ketoesters, aromatic aldehydes, and various amines using p-sulfonic acid calix[n]arenes as catalysts. The reaction was carried out in refluxing methanol, affording very good yields of the expected piperidine. Atomic economy, environmentally benign procedure, reuse of catalysts, and short reaction time are some of the important features of this protocol. |
Palavras-chave: | Densely functionalized piperidines p-Sulfonic acid calix[n]arenes Heterocyclic Multicomponent reactions Organocatalysts |
Editor: | Tetrahedron Letters |
Tipo de Acesso: | Elsevier Ltd |
URI: | https://doi.org/10.1016/j.tetlet.2016.03.090 http://www.locus.ufv.br/handle/123456789/21315 |
Data do documento: | 11-Mai-2016 |
Aparece nas coleções: | Artigos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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artigo.pdf Until 2100-12-31 | texto completo | 539,21 kB | Adobe PDF | Visualizar/Abrir ACESSO RESTRITO |
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