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  • Mairink, Simone Z.; Barbosa, Luiz C. A.; Boukouvalas, John; Pedroso, Silvia H. S. P.; Magalhães, Paula P.; Farias, Luiz M.; Santos, Simone G. (Medicinal Chemistry Research, 2018-12)
    Bacterial biofilm infections pose a major clinical challenge due to the ability of biofilms to resist high levels of conventional antibiotics. In the present study, we describe the synthesis and biofilm inhibiting properties ...
  • Alvarenga, E.S. de; Silva, S.A.; Barosa, L.C.A.; Demuner, A.J.; Parreira, A.G.; Ribeiro, R.I.M.A.; Marcussi, S.; Ferreira, J.M.S.; Resende, R.R.; Granjeiro, P.A.; Silva, J.A.; Soares, A.M.; Marangoni, S.; Silva, S.L. Da (Toxicon, 2010-10-31)
    Several sesquiterpene lactone were synthesized and their inhibitive activities on phospholipase A2 (PLA2) from Bothrops jararacussu venom were evaluated. Compounds Lac01 and Lac02 were efficient against PLA2 edema-inducing, ...
  • Santos, Marcelo H. dos; Rosa, Isael A.; Almeida, Letícia de; Alves, Karina F.; Marques, Marcos J.; Fregnan, Antônio M.; Silva, Claudinei A.; Giacoppo, Juliana O. S.; Carvalho, Diogo T.; Ramalho, Teodorico C. (Medicinal Chemistry Research, 2016-10-27)
    Eight coumarin derivatives (2–8) were synthesized from 7-hydroxy-4-phenylcoumarin 1 and were evaluated for their in vitro leishmanicidal activity against promastigote and amastigote forms of Leishmania amazonensis, as well ...
  • Teixeira, Róbson Ricardo; Gazolla, Poliana Aparecida Rodrigues; Silva, Adalberto Manoel da; Borsodi, Maria Paula Gonçalves; Bergmann, Bartira Rossi; Ferreira, Rafaela Salgado; Vaz, Boniek Gontijo; Vasconcelos, Géssica Adriana; Lima, Wallace Pacienza (European Journal of Medicinal Chemistry, 2018-01-15)
    In this paper, it is described the synthesis and the evaluation of the leishmanicidal activity of twenty-six eugenol derivatives bearing 1,2,3-triazole functionalities. The evaluation of the compounds on promastigotes of ...
  • Resende, Gabriela C.; Alvarenga, Elson S.; Galindo, Juan C. G.; Macias, Francisco A. (Journal of the Brazilian Chemical Society, 2012-12)
    In this work we report a versatile synthesis of fourteen γ-lactones all structurally related, nine of which are novel compounds, accomplished from the readily available furfural. The phytotoxic activity of the synthesized ...
  • Barbosa, L. C. A.; Kiran, Y. B.; Gunasekar, D.; Raju, C. Naga; Marney, D. C. O.; Reddy, C. Devendranath; Russell, L. J. (Journal of Fire Sciences, 2007-05)
    Several new substituted organo tri/thiotriphosphate esters were synthesized by condensing cyclic oxaza/dioxaphosphorochloridates/thiochloridates with [K.sub.2]HP[O.sub.4] in the presence of tetrabutylammonium iodide. The ...
  • Barbosa, Luiz C de A; Alvarenga, Elson S de; Demuner, Antônio J; Figueiredo, Remilson; Silva, Antônio A da (Pest Management Science, 2003-06-11)
    Several new compounds with potential herbicidal activity were synthesized from 2α,4α-dimethyl-6,7-exo-isopropylidenedioxy-8-oxabicyclo[3.2.1]octan-3-one (4). Seven aromatic alcohols were prepared by reaction of (4) with ...
  • Barbosa, Luiz Cláudio de Almeida; Alvarenga, Elson Santiago de; Demuner, Antônio Jacinto; Virtuoso, Luciano Sindra; Silva, Antônio Alberto (Chemistry & Biodiversity, 2006-05-23)
    Reaction of [(2-alkyloxy)methyl]-1,4-dimethoxybenzene 10 (alkyl=butyl, hexyl, decyl, tridecyl, tetradecyl, hexadecyl, and octadecyl) with ceric ammonium nitrate in order to produce p-benzoquinones (=cyclohexa-2,5-diene-1,4-diones) ...
  • Costa, Adilson Vidal; Oliveira, Marcos Vinicius Lacerda de; Pinto, Roberta Tristão; Moreira, Luiza Carvalheira; Gomes, Ediellen Mayara Corrêa; Alves, Thammyres de Assis; Pinheiro, Patrícia Fontes; Queiroz, Vagner Tebaldi de; Vieira, Larissa Fonseca Andrade; Teixeira, Robson Ricardo; Jesus Júnior, Waldir Cintra de (Molecules, 2017-10-07)
    The synthesis of a series of 1,2,3-triazoles using glycerol as starting material is described. The key step in the preparation of these triazolic derivatives is the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), ...
  • Arantes, Francisco F.P.; Barbosa, Luiz C.A.; Maltha, Célia R.A.; Demuner, Antônio J.; Costa, PatriciaMarçal da; Ferreira, José R.O.; Costa-Lotufo, Letícia V.; Moraes, Manoel O.; Pessoa, Cláudia (European Journal of Medicinal Chemistry, 2010-10-23)
    Ten novel a -santonin derivatives have been synthesized as cytotoxic agents. The in vitro antitumor activity of these compounds has been evaluated against cancer cells lines. Structure-activity relationships indicate that ...
  • Nascimento, Mayra A.; Cruz, Jean C.; Oliveira, André F. de; Lopes, Renata P.; Rodrigues, Guilherme D. (Journal of Cleaner Production, 2018-11-20)
    In this study inedited polymetallic nanoparticles were synthesized from electronic wastes of spent lithium-ion batteries (PN-LIB) and applied in the removal of the dye reactive blue 4 (RB4). Initially, the extraction of ...
  • Santos, Marcelo Henrique dos; Hipólito, Taciane Maíra Magalhães; Bastos, Guilherme Tadeu Lemos; Barbosa, Thúlio Wliandon Lemos; Souza, Thiago Belarmino de; Coelho, Luiz Felipe Leomil; Dias, Amanda Latércia Tranches; Rodríguez, Ihosvany Camps; Dias, Danielle Ferreira; Franco, Lucas Lopardi; Carvalho, Diogo Teixeira (Chemical Biology & Drug Design, 2018-04-25)
    Seventeen new synthetic derivatives of eugenol (6, 8–15 and 8′‐15′) were planned following literature reports on antifungal activities of nitroeugenol and eugenol glucoside. The anti‐Candida activity of these compounds was ...
  • Maia, José R. da S.; Vieira, Flaviana T.; Lima, Geraldo M. de; Speziali, Nivaldo L.; Ardisson, José D.; Rodrigues, Leonardo; Correa Junior, Ary; Romero, Oscar B. (European Journal of Medicinal Chemistry, 2010-03)
    The reaction of 1,3-cyclohexadione with 2-aminobenzoic acid has produced the 2-(3-oxocyclohex-1-enyl)benzoic acid (HOBz). Subsequent reactions of the ligand with organotin chlorides led to [Me2Sn(OBz)O]2 (1), [Bu2Sn(OBz)O]2 ...
  • Santos, Marcelo Henrique Dos; Gonçalves, Cristiane Batista; Marinho, Maria Vanda; Dias, Danielle Ferreira; Martins, Felipe Terra; Doriguetto, Antônio Carlos (Journal of Coordination Chemistry, 2017)
    Four mononuclear copper(II) complexes, [Cu(LFQM-115)2] (1), [Cu(LFQM-116)2] (2), [Cu(LFQM-117)2] (3) and [Cu(octyloxy)2] (4) [LFQM-115 = 2-hydroxy-4-O-methylbenzophenone (C14H11O3), LFQM-116 = 2-hydroxy-4-O-butylbenzophenone ...
  • Aguiar, Alex R.; Alvarenga, Elson S.; Silva, Eliete M. P.; Farias, Elizeu S.; Picanço, Marcelo C. (Pest Management Science, 2019)
    The lesser grain borer, Rhyzopertha dominica (F.) (Coleoptera: Bostrychidae), is an important pest of stored grains worldwide. Chemical control is the main method used to manage this pest, but the continuous use of ...
  • Oliveira, Fabricio M.; Barbosa, Luiz C. A.; Demuner, Antônio J.; Maltha, Célia R. A.; Pereira, Silvana R.; Horta, Lı́via P.; Modolo, Luzia V. (Medicinal Chemistry Research, 2014-06-28)
    In this work, new phosphoramidates were prepared and screened for their putative urease inhibitory activity. The importance of this class of compounds is related to the wide range of biological activities which they exhibit. ...
  • Maia, Angélica Faleiros da Silva; Siqueira, Raoni Pais; Oliveira, Fabrício Marques de; Ferreira, Joana Gasperazzo; Silva, Silma Francielle da; Caiuby, Clarice Alves Dale; Oliveira, Leandro Licursi de; Paula, Sérgio Oliveira de; Souza, Rafael Aparecido Carvalho; Guilardi, Silvana; Bressan, Gustavo Costa; Teixeira, Róbson Ricardo (Elsevier Bioorganic & Medicinal Chemistry Letters, 2016-04-25)
    In the present investigation, a collection of nineteen 3-(2-aryl-2-oxoethyl)isobenzofuran-1(3H)-ones was synthesized and screened for their cytotoxic activity against a panel of three leukemia cancer cell lines. The compounds ...
  • Oliveira, Marcelo R. L.; Perpetuo, Genivaldo J.; Janczak, Jan; Rubinger, Mayura M. M. (Polyhedron, 2007-01-02)
    Two new zinc(II)-complexes, dithiocarbimato (Ph4P)2[Zn(CH3SO2N=CS2)2] (1) and trithiocarbimato (Ph4P)2[Zn(CH3SO2N=CS3)2] (2), were obtained in the crystalline form by the reaction of potassium N-methylsulfonyldithiocarbimate ...
  • Teixeira, Róbson Ricardo; Barros, Marcus Vinícius de Andrade; Bressan, Gustavo Costa; Siqueira, Raoni Pais; Santos, Fabíola Suelen dos; Bertazzini, Michele; Kiralj, Rudolf; Ferreira, Márcia Miguel Castro; Forlani, Giuseppe (Pest Management Science, 2017-05-25)
    The photosynthetic apparatus is targeted by various herbicides, including several amides such as diuron and linuron. Considering the need for the discovery of new active ingredients to cope with weed resistance, the synthesis ...
  • Teixeira, Róbson Ricardo; Pereira, Wagner Luiz; Tomaz, Deborah Campos; Oliveira, Fabrício Marques de; Giberti, Samuele; Forlani, Giuseppe (Journal of Agricultural and Food Chemistry, 2013-05-17)
    A series of isobenzofuran-1(3H)-ones (phthalides), analogues of the naturally occurring phytotoxin cryphonectric acid, were designed, synthesized, and fully characterized by NMR, IR, and MS analyses. Their synthesis was ...

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