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Shannon entropy of brain functional complex networks under the influence of the psychedelic Ayahuasca

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dc.contributor.author Viol, A.
dc.contributor.author Palhano-Fontes, Fernanda
dc.contributor.author Onias, Heloisa
dc.contributor.author Araujo, Draulio B. de
dc.contributor.author Viswanathan, G. M.
dc.date.accessioned 2017-10-11T11:12:19Z
dc.date.available 2017-10-11T11:12:19Z
dc.date.issued 2017-08-07
dc.identifier.issn 2045-2322
dc.identifier.uri http://dx.doi.org/10.1038/s41598-017-06854-0
dc.identifier.uri http://www.locus.ufv.br/handle/123456789/12003
dc.description.abstract The entropic brain hypothesis holds that the key facts concerning psychedelics are partially explained in terms of increased entropy of the brain’s functional connectivity. Ayahuasca is a psychedelic beverage of Amazonian indigenous origin with legal status in Brazil in religious and scientific settings. In this context, we use tools and concepts from the theory of complex networks to analyze resting state fMRI data of the brains of human subjects under two distinct conditions: (i) under ordinary waking state and (ii) in an altered state of consciousness induced by ingestion of Ayahuasca. We report an increase in the Shannon entropy of the degree distribution of the networks subsequent to Ayahuasca ingestion. We also find increased local and decreased global network integration. Our results are broadly consistent with the entropic brain hypothesis. Finally, we discuss our findings in the context of descriptions of “mind-expansion” frequently seen in self-reports of users of psychedelic drugs. en
dc.format pdf pt-BR
dc.language.iso eng pt-BR
dc.publisher Scientific Reports pt-BR
dc.relation.ispartofseries 7: 7388 August 2017 pt-BR
dc.rights Open Access pt-BR
dc.subject Influence of the psychedelic pt-BR
dc.subject Ayahuasca pt-BR
dc.title Shannon entropy of brain functional complex networks under the influence of the psychedelic Ayahuasca en
dc.type Artigo pt-BR


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  • Artigos [160]
    Artigos Técnico-científicos na área de Física

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