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Immunopathogenic and neurological mechanisms of canine distemper virus

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dc.contributor.author Carvalho, Otávio Valério
dc.contributor.author Botelho, Clarisse Vieira
dc.contributor.author Ferreira, Caroline Gracielle Torres
dc.contributor.author Scherer, Paulo Oldemar
dc.contributor.author Soares-Martins, Jamária Adriana Pinheiro
dc.contributor.author Almeida, Márcia Rogéria
dc.contributor.author Júnior, Abelardo Silva
dc.date.accessioned 2017-10-18T15:40:58Z
dc.date.available 2017-10-18T15:40:58Z
dc.date.issued 2012-10-11
dc.identifier.issn 1687-8639
dc.identifier.uri http://dx.doi.org/10.1155/2012/163860
dc.identifier.uri http://www.locus.ufv.br/handle/123456789/12145
dc.description.abstract Canine distemper is a highly contagious viral disease caused by the canine distemper virus (CDV), which is a member of the Morbillivirus genus, Paramyxoviridae family. Animals that most commonly suffer from this disease belong to the Canidae family; however, the spectrum of natural hosts for CDV also includes several other families of the order Carnivora. The infectious disease presents worldwide distribution and maintains a high incidence and high levels of lethality, despite the availability of effective vaccines, and no specific treatment. CDV infection in dogs is characterized by the presentation of systemic and/or neurological courses, and viral persistence in some organs, including the central nervous system (CNS) and lymphoid tissues. An elucidation of the pathogenic mechanisms involved in canine distemper disease will lead to a better understanding of the injuries and clinical manifestations caused by CDV. Ultimately, further insight about this disease will enable the improvement of diagnostic methods as well as therapeutic studies. en
dc.format pdf pt-BR
dc.language.iso eng pt-BR
dc.publisher Advances in Virology pt-BR
dc.relation.ispartofseries Volume 2012 , Article ID 163860, October 2012 pt-BR
dc.rights Open Access pt-BR
dc.subject Immunopathogenic pt-BR
dc.subject Neurological pt-BR
dc.subject Distemper Virus pt-BR
dc.title Immunopathogenic and neurological mechanisms of canine distemper virus en
dc.type Artigo pt-BR


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  • Artigos [566]
    Artigos Técnico-científicos na área de Veterinária

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