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Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise

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dc.contributor.author Melo, Stéphano Freitas Soares
dc.contributor.author Lunz, Wellington
dc.contributor.author Fontes, Elizabeth Pacheco Batista
dc.contributor.author Dias, Cristina Maria Ganns Chaves
dc.contributor.author Moura, Anselmo Gomes de
dc.contributor.author Carlo, Ricardo Junqueira Del
dc.contributor.author Natali, Antonio Jose
dc.contributor.author Carneiro Júnior, Miguel Araujo
dc.date.accessioned 2017-10-30T14:15:56Z
dc.date.available 2017-10-30T14:15:56Z
dc.date.issued 2008-12-02
dc.identifier.issn 0066-782X
dc.identifier.uri http://dx.doi.org/10.1590/S0066-782X2009001100004
dc.identifier.uri http://www.locus.ufv.br/handle/123456789/12504
dc.description.abstract Physical exercise induces hemodynamic stress. To evaluate if voluntary running and forced running induced different levels of stress protein (Hsp72) in the myocardium of female Wistar rats. Female rats were randomly assigned to the following groups: forced treadmill running group (FR; n= 6), voluntary running group (VR; n=6) and control group (C; n=6). VR group animals had free access to running wheels, and those from FR group underwent a running program on a treadmill (18 m/min, 60 min/day, 5 days/wk) for 8 weeks. Left ventricle (LV) and right ventricle (RV) fragments were collected at sacrifice, and the relative immunoblot contents of stress protein (Hsp72) were determined. VR animals ran on average 4.87 km/wk, and FR rats ran 4.88 km/wk. Animals from VR and FR groups had less body weight gain (p<0.05) than those from C group (81.67 ± 11.95g vs 81.17 ± 10.18g vs 111.50 ± 2.26g, respectively). Heart weight/body weight ratio was not significantly different (p>0.05) among VR, FR and C groups (4.54 ± 0.79 mg/g vs 4.94 ± 0.89 mg/g vs 4.34 ± 0.87 mg/g, respectively). FR group animals had levels of Hsp72 (p<0.05) higher than those from VR, both in LV (287.45 ± 35.86 % vs 135.59 ± 5.10 %, respectively) and RV (241.31 ± 25.83 % vs 137.91 ± 45.20 %, respectively). Voluntary running and forced running induced different levels of Hsp72 in the myocardium of female Wistar rats. en
dc.format pdf pt-BR
dc.language.iso eng pt-BR
dc.publisher Arquivos Brasileiros de Cardiologia pt-BR
dc.relation.ispartofseries 93(5), p. 423-429, 2009 pt-BR
dc.rights Open Access pt-BR
dc.subject Physical activity pt-BR
dc.subject Running pt-BR
dc.subject Rats pt-BR
dc.subject Stress pt-BR
dc.subject Myocardium pt-BR
dc.title Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise en
dc.type Artigo pt-BR


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  • Artigos [124]
    Artigos Técnico-científicos na área de Educação Física

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