Aedes aegypti midgut remodeling during metamorphosis

Show simple item record Fernande, Kenner Morais Neves, Clóvis Andrade Serrão, José Eduardo Martins, Gustavo Ferreira 2018-04-04T10:51:46Z 2018-04-04T10:51:46Z 2014-01-26
dc.identifier.issn 13835769
dc.description.abstract The Aedes aegypti midgut is restructured during metamorphosis; its epithelium is renewed by replacing the digestive and endocrine cells through stem or regenerative cell differentiation. Shortly after pupation (white pupae) begins, the larval digestive cells are histolized and show signs of degeneration, such as autophagic vacuoles and disintegrating microvilli. Simultaneously, differentiating cells derived from larval stem cells form an electron-dense layer that is visible 24 h after pupation begins. Forty-eight hours after pupation onset, the differentiating cells yield an electron-lucent cytoplasm rich in microvilli and organelles. Dividing stem cells were observed in the fourth instar larvae and during the first 24 h of pupation, which suggests that stem cells proliferate at the end of the larval period and during pupation. This study discusses various aspects of the changes during midgut remodeling for pupating A. aegypti. en
dc.format pdf pt-BR
dc.language.iso eng pt-BR
dc.publisher Parasitology International pt-BR
dc.relation.ispartofseries v. 63, Issue 3, p. 506-512, June 2014 pt-BR
dc.rights Elsevier Ireland Ltd. All rights reserved. pt-BR
dc.subject Midgut pt-BR
dc.subject Development pt-BR
dc.subject Aedes aegypti pt-BR
dc.subject Endocrine cells pt-BR
dc.subject Stem cells pt-BR
dc.subject Regenerative cells pt-BR
dc.title Aedes aegypti midgut remodeling during metamorphosis en
dc.type Artigo pt-BR

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    Artigos Técnico-científicos na área de Biologia Geral

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