Use este identificador para citar ou linkar para este item: https://locus.ufv.br//handle/123456789/22507
Tipo: Artigo
Título: Evaluation of metoclopramide and ranitidine on the prevention of gastroesophageal reflux episodes in anesthetized dogs
Autor(es): Favarato, E. S.
Souza, M. V.
Costa, P. R. S.
Nehme, R. C.
Monteiro, B. S.
Bonfá, L. P.
Favarato, L. S. C.
Abstract: This research aimed to evaluate the effect of metoclopramide and ranitidine in the prevention of gastroesophageal reflux episodes during anesthetic procedures. Ninety healthy female dogs were submitted to elective ovariosalpingohisterectomy, randomly divided into three groups of 30 animals. The control group received only the anesthetic protocol. The metoclopramide group received an intravenous bolus of 1 mg/kg, and continuous infusion (1 mg/kg/h intravenously) immediately after anesthetic induction. The ranitidine group received an intravenous bolus of 2 mg/kg, 6 h before anesthesia. Anesthesia (acepromazine, propofol and isofluorane) was standardized and the esophageal pH variations were recorded. Esophagoscopy was carried out after surgery. No difference (p < 0.05) was verified in the reflux episodes between the groups. Seven animals presented reflux. Metoclopramide in bolus and continuous infusion, as well as ranitidine, 6 h before anesthesia, did not influence the reduction of the incidence of gastroesophageal reflux.
Palavras-chave: Esophageal pHmetry
Esophagoscopy
Esophagitis
Prokinetic drug
Anesthesia
H2 receptor antagonist
Editor: Research in Veterinary Science
Tipo de Acesso: Elsevier Ltd. All rights reserved.
URI: https://doi.org/10.1016/j.rvsc.2011.07.027
http://www.locus.ufv.br/handle/123456789/22507
Data do documento: Ago-2012
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